Publications

 

Safarian N, Whyte-Fagundes P, Zoidl C, Grigull J, Zoidl G (2020) Visuomotor deficiency in panx1a knockout zebrafish is linked to dopaminergic signaling. Scientific Reports 10(1): 9538.

Tobin SW, Hashemi S, Dadson K, Turdi S, Ebrahimian K, Zhao J, Sweeney G, Grigull J, McDermott JC (2017) Heart failure and MEF2 transcriptome dynamics in response to β-blockers. Scientific Reports 7(1): 4476.

Mughal W, Nguyen L, Pustylnik S, da Silva Rosa SC, Pietrowski S, Chapman D, Du M, Alli NS, Grigull J, Halayko AJ, Topham MK, Epand RM, Hatch GM, Pereira TJ, Kereliuk S, McDermott JC, Rampitsch C, Dolinsky VW, and Gordon JW (2015) A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac, and smooth muscle cells. Cell Death & Disease Oct. 29; 6:e1944.

Ashton P, Wu B, D’Angelo J, Grigull J, White KA (2015) Biologically-supported structural model for a viral satellite RNA. Nucleic Acids Research 43(20):9965-77.

Chen L, Duvvuri B, Grigull J, Jamnik R, Wither JE, Wu GE (2014) Experimental evidence that self-mutated self-peptides derived from mitochondrial DNA somatic mutations have the potential to trigger autoimmunity. Human Immunology 75(8): 873-879.

Duvvuri B, Duvvuri VR, Wang C, Chen L, Wagar LE, Jamnik V, Wu J, Yeung RS, Grigull J, Watts TH, Wu GE (2014) The human immune system recognizes neopeptides derived from mitochondrial DNA deletions. Journal of Immunology 192(10): 4581-4591.

2011-2013:

Wu B, Grigull J, Ore MO, Morin S, White A (2013) Global organisation of a positive-strand RNA virus genome. PLoS Pathogens 9(5): e1003363.

White NMA, Khella HBZ, Grigull J, Bao TT, Youssef MY, Honey RJ, Stewart R, Pace KT, Bjarnason GA, Jewett MAS, Evans AJ, Gabril M, Yousef GM (2011) miRNA profiling in metastatic renal cell carcinoma reveals a tumor suppressor effect for miR-215. British Journal of Cancer 105: 1741-1749.

Youssef MY, White NMA, Grigull J, Krizova A, Samy C, Meija-Guerrera, Evans A, Yousef GM (2011) Accurate molecular classification of kidney cancer subtypes using microRNA signature. European Urology (2011) 59: 721-730

Tripathi SC, Matta A, Kaur J, Grigull J, Chauhan SS, Thakar A, Shukla NK, Duggal R, Choudhary AR, Dattagupta S, Sharma MC, Ralhan R, Siu KW (2011) Overexpression of prothymosin alpha predicts poor disease outcome in head and neck cancer. PLoS One 6(5): e19213

White N, Bao T, Grigull J, Youssef Y, Diamandis M, Fattohi E, Mejia-Guerrero S,  Metias M, Honey R, Stewart R, Pace K, Bjarnason G,Yousef G (2011) MiRNA  profiling in clear cell renal cell carcinoma: A comprehensive experimental and bioinformatic analysis. Journal of Urology 186: 1077-1083.

Duvvuri B, Duvvuri VR, Grigull J, Martin A, Pan-Hammarström Q, Wu GE, Larijani M (2011) Altered spectrum of somatic hypermutation in common variable immunodeficiency disease characteristic of defective repair of mutations. Immunogenetics  63: 1-11

2006-2010:

Tripathi SC, Matta A, Kaur J, Grigull J, Chauhan SS, Thakar A, Shukla NK, Duggal R, DattaGupta S, Ralhan R, Siu KWM (2010) Nuclear S100A7 is associated with poor prognosis in head and neck cancer.             PLoS One 5(8):e11939.

Matta A, Tripathi SC, DeSouza LV, Grigull J, Kaur J, Chauhan SS, Srivastava A, Thakar A, Shukla NK, Duggal R, DattaGupta S, Ralhan R, Siu KWM (2009) Heterogeneous ribonucleoprotein K is a marker of oral leukoplakia and correlates with poor prognosis of squamous cell carcinoma. Int J Cancer 125(6): 1398-1406.

Miao W, Xiong J, Bowen J, Wang W, Liu Y, Braguinets O, Grigull J, Pearlman RE, Orias E, Gorovsky MA. Microarray analyses of gene expression during the Tetrahymena thermophila life cycle. PLoS ONE. 2009;4(2):e4429. Epub 2009 Feb 10.

DeSouza LV, Grigull J, Ghanny S, Dube V, Romaschin AD, Colgan TJ, Siu KWM (2007) Endometrial carcinoma biomarker discovery and verification using  differentially tagged clinical samples with multidimensional liquid chromatography and tandem mass spectrometry. Mol Cell Proteomics 6(7): 1170-1182.

Dube V, Grigull J, Desouza LV, Ghanny S, Colgan TJ, Romaschin AD, Siu KWM (2007) Verification of endometrial tissue biomarkers previously discovered using mass spectrometry-based proteomics by means of immunohistochemistry in a tissue microarray format. J Proteome Res 6(7): 2648-2655.

2005 and earlier:

Grigull J, Mnaimneh S, Pootoolal J, Robinson MD, and Hughes TR (2004) Genome-wide analysis of mRNA stability using transcription inhibitors and microarrays reveals posttranscriptional control of ribosome biogenesis factors. Mol Cell Biol 24: 5534-47.

Zhang W, Morris QD, Chang R, Shai O, Bakowski MA, Mitsakakis N, Mohammad N, Robinson MD, Zirnglibl R, Somogyi E, Eftekharpour E, Sat E, Grigull J, Pan Q, Peng WT, Krogan N, Greenblatt J, Fehlings M, van der Kooy D, Aubin J, Bruneau BG, Rossant J, Blencowe BJ, Frey BJ, and Hughes TR (2004) The functional landscape of mouse gene expression. J Biol 3: 21

Mnaimneh S, Davierwala AP, Haynes J, Moffat J, Peng WT, Zhang W, Yang X, Pootoolal J, Chua G, Lopez A, Trochesset M, Morse D, Krogan NJ, Hiley SL, Li Z, Morris Q, Grigull J, Mitsakakis N, Roberts CJ, Greenblatt JF, Boone C, Kaiser CA, Andrews BJ, and Hughes TR (2004) Exploration of essential gene functions via titratable promoter alleles.Cell 118: 31-44.

Krogan NJ, Peng WT, Cagney G, Robinson MD, Haw R, Zhong G, Guo X, Zhang X, Canadien V, Richards DP, Beattie BK, Lalev A, Zhang W, Davierwala AP, Mnaimneh S, Starostine A, Tikuisis AP, Grigull J, Datta N, Bray JE, Hughes TR, Emili A, Greenblatt JF (2004) High-definition macromolecular composition of yeast RNA-processing complexes.Mol Cell 13: 225-239.

Jalil S1, Grigull J1, and Skinner FK (1: co-lead authors) (2004) Novel bursting patterns emerging from inhibitory networks with synaptic depression. J Comput Neurosci 17: 31-45.

Peng, W-T, Robinson, MD, Mnaimneh S, Krogan N, Cagney G, Morris Q, Davierwala AP, Grigull J, Yang X, Zhang W, Mitsakakis N, Ryan OW, Datta N, Jojic V, Pal C, Canadien V, Richards D, Beattie B, Wu, LF, Altschuler SJ, Boone C, Roweis S, Frey BJ, Emili A, Greenblatt J, and Hughes TR (2003). A panoramic view of yeast noncoding RNA processing. Cell 113: 919-33.

Grigull J, and Skinner F (2003) The effect of synaptic depression on model inhibitory networks. Canad Appl Math Quart 10: 87-110.

Robinson M, Grigull J, Naveed M, and Hughes TR (2002) FunSpec: A web-based tool for statistical functional enrichment testing. BMC Bioinformatics 3:35.

Grigull J, Alexandrova A, and Paterson A (2001) Clustering of pedigrees using marker allele frequencies: impact on linkage analysis. Genet Epidemiol 21, Suppl S1: 61-66.

Clarke AH, Grigull J, Mueller R, and Scherer H (2000) The three-dimensional vestibuloocular reflex during prolonged microgravity. Exp Brain Res 134: 322-334.